Jens Damsgaard Mikkelsen

This study examines changes in P2X7R binding in a rat epilepsy model, showing region-specific and time-dependent increases linked to neuroinflammation and chronic epilepsy.

This study validates 5-MOP as a highly selective CSF1R radioligand with nanomolar affinity, enabling accurate detection of drug occupancy and microglial activation.

This study shows that astroglial TNFR2 signaling is crucial for hippocampal synaptic function and plasticity, with more pronounced effects in males.

The paper evaluates MAGL levels in epileptic brains using [3H]T-401 binding, finding reduced MAGL in multiple brain regions in both human patients and mice.

This study evaluates the efficacy and safety of 5-HT1A and 5-HT1B/D agonists in reducing L-DOPA-induced dyskinesia in a rat model, finding synergistic effects and superior performance compared to amantadine.

This study compares [11C]UCB-J and [18F]FDG PET in a 6-OHDA rat model of Parkinson's disease, finding divergent changes in synaptic density and metabolic function in CSTC circuits.