Author

Kate Lykke Lambertsen

University of Southern DenmarkORCID 0000-0001-9276-4902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Burcu Azak PazarlariD· 2 shared Jens Damsgaard MikkelseniD· 2 shared Agnieszka WłodarczykiD· 1 shared Amy F. LloydiD· 1 shared Andoni I. AsencoriD· 1 shared Anne Marlene LandauiD· 1 shared Anouk Benmamar‐BadeliD· 1 shared Antonella MiniiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersNeuroscience

Burcu Azak PazarlarORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Selective targeting of the oligodendroglial GPR17 receptor improves myelin integrity and motor function in female SOD1G93A mice

Stefano Raffaele, Tiziana Bonifacino, Francesca Carolina Mannella, Nhung Nguyen, Carola Torazza, Davide Marangon, Elena Maria Chinosi, Henrik Daa Schrøder, Eva Kildall Hejbøl, Kirsten Madsen, Laura Marchetti, Maria Letizia Trincavelli, Marco Milanese, Davide Lecca, Kate Lykke Lambertsen, , Marta Fumagalli

This study shows that targeting GPR17 in oligodendrocytes improves myelin and motor function in female ALS mice but not males.

Pharmacological Research · Sep 1, 2026Peer-reviewedPharmacology & Toxicology

5-MOP: a novel and selective colony stimulating factor-1 receptor (CSF1R) radiotracer

Camilla Iavazzo, Burcu Azak Pazarlar, Benny Bang‐Andersen, Thomas N. Jensen, Morten Hentzer, Jesper F. Bastlund, Kate Lykke Lambertsen, Bente R. Finsen, Anne Marlene Landau, Jens Damsgaard Mikkelsen

This study validates 5-MOP as a highly selective CSF1R radioligand with nanomolar affinity, enabling accurate detection of drug occupancy and microglial activation.

bioRxiv · May 14, 2026 · PreprintNeuroscience

Astroglial TNFR2 signaling regulates hippocampal synaptic function and plasticity in a sex dependent manner

Brianna N Carney, Placido Illiano, Taylor M. Pohl, Haritha L. Desu, Antonella Mini, Shwetha Mudalegundi, Andoni I. Asencor, Shika Jwala, Maureen C. Ascona, Praveen Kumar Singh, David J. Titus, Burcu Azak Pazarlar, Lei Wang, Laura K. Bianchi, Jens Damsgaard Mikkelsen, , Roberta Brambilla

This study shows that astroglial TNFR2 signaling is crucial for hippocampal synaptic function and plasticity, with more pronounced effects in males.

Brain, Behavior, and Immunity · Oct 1, 2025Peer-reviewedNeuroscience

Neonatal Microglia and Their Secretome as Mediators of Brain Repair

Gabriela Łyszczarz, Eydís Sigurðardóttir Schiöth, Anouk Benmamar‐Badel, Dominika Rusin, David Ramonet, Marco Anzalone, Thalissa Caers, Lejla Vahl Becirovic, Kirstine Nolling Jensen, Sanne G. S. Verberk, Fleur Mingneau, Martyna Makowska, Kate Lykke Lambertsen, Amy F. Lloyd, Jerome J. A. Hendriks, Agnieszka Włodarczyk

This study shows neonatal microglia improve brain repair in aged mice through secreted factors, highlighting the potential of early microglial programs for regenerative therapies.

bioRxiv · Sep 21, 2025 · PreprintNeuroscience