Author

Karen S. Moulton

University of Colorado AnschutzORCID 0000-0001-9836-6614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Allison DubneriD· 2 shared Austin JollyiD· 2 shared Raphael A. NemenoffiD· 2 shared Sizhao LuiD· 2 shared Amber M. Johnson· 1 shared Andre NavarroiD· 1 shared Brisa PeñaiD· 1 shared Elizabeth J. HardyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Allison DubnerORCID

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2 papers

Recent·Most cited

Cell BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedAug 20, 2026

KLF4 in smooth muscle cell-derived progenitor cells is essential for angiotensin II-induced cardiac inflammation and fibrosis

Sizhao Lu, Tysen Noble, Jake Elkins…·Mary C.M. Weiser‐Evans

This study shows that KLF4 in smooth muscle cell-derived progenitor cells drives AngII-induced cardiac inflammation and fibrosis by promoting a profibrotic phenotype.

1 citation

mousescRNA-seq

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Cancer BiologybioRxivPreprintMay 30, 2025

Klf4-dependent pivotal role of smooth muscle-derived Gli1+ lineage progenitor cells in lung cancer progression

Sizhao Lu, Andre Navarro, Amber M. Johnson…·Mary C. M. Weiser-Evans

This study identifies AdvSca1-SM cells as a key component of lung tumors and shows that Klf4-dependent regulation of these cells affects cancer progression and immunotherapy response.

DOI 10.1101/2025.05.30.657094

mouseexperimental assay

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