PhysiologybioRxivPreprint
Meclizine rescues cardiac function and mitochondrial ultrastructure by ATP- and glycolysis-independent mechanisms in a genetic model of mitochondrial energy dysfunction
Nasab Ghazal, Benjamin Xiongzheng Huang, Luke J. Shoemaker…·Jennifer Q. Kwong
This study shows meclizine improves cardiac function and mitochondrial structure in a mitochondrial disease model without relying on ATP or glycolysis.
DOI 10.1101/2025.09.03.674000