Atomic structure and dynamics of the mechanosensitive channel MscL from E. coli by cryo-EM and solid-state NMR
Taoran Xiao, Alexandra Kovinko, Chaowei Shi, Henry Sawczyc, Denis Qoraj, Carl Öster, Thiemo Sprink, Sascha Lange, Spyridon Kosteletos, Han Sun, Daniel Roderer, Shanshuang Chen, Adam Lange
This study uses cryo-EM and solid-state NMR to determine the structure and dynamics of MscL from E. coli, revealing lipid-protein interactions that drive mechanosensitive gating.
bioRxiv · Apr 15, 2026 · PreprintBiophysics