BiophysicsiSciencePeer-reviewed
The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.
Yevhenii A. Kyriukha, Maxwell B. Watkins, Jennifer Redington…·Sergey Korolev
This study identifies the PALB2 DNA-binding domain as an intrinsically disordered region that promotes DNA compaction through oligomerization, revealing a novel strand exchange mechanism.
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