Author

Ivan Spasojević

Duke Cancer InstituteORCID 0000-0001-9890-6246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam L. GreeniD· 1 shared Daniel Jay BratiD· 1 shared Dolores HambardzumyaniD· 1 shared Eita UchidaiD· 1 shared Emma R.H. GoldiD· 1 shared Evan CalabreseiD· 1 shared Flávio H. BeraldoiD· 1 shared G. Allan JohnsoniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Adam L. GreenORCID

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2 papers

Recent·Most cited

Cancer BiologyPLoS ONEPeer-reviewedDec 22, 2025

Effects of Combination Therapy of a CDK4/6 and MEK Inhibitor in Diffuse Midline Glioma Preclinical Models

Yusuke Tomita, Gabrielle Link, Yi Ge…·Oren Josh Becher

This study evaluates combination therapy of CDK4/6 and MEK inhibitors in DMG models, finding survival benefits in GEM but not PDX models.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceeNeuroPeer-reviewedSep 1, 2022

Measuring nonapoptotic caspase activity with a transgenic reporter in mice

PETER J. NICHOLLS, Thomas F. Pack, Nikhil M. Urs…·Marc G. Caron

The paper develops a transgenic mouse model with a fluorescent caspase activity reporter to quantify nonapoptotic caspase activity in rodent brains and demonstrates its use in studying neurophysiological and stress-related effects.

4 citations

𝕏 PostBluesky