Marc G. Caron

This study shows that combining haloperidol with UNC9994 reduces schizophrenia-like symptoms in NMDAR-deficient mice.

This paper establishes a multi-stage IVSA paradigm in mice for studying addiction, showing that behavioral traits predict vulnerability to drug seeking and relapse.

The paper develops a transgenic mouse model with a fluorescent caspase activity reporter to quantify nonapoptotic caspase activity in rodent brains and demonstrates its use in studying neurophysiological and stress-related effects.

This study shows that loss of β-arrestin2 in D2 neurons reduces dopamine inhibition of D2-MSNs and alters behavioral responses to psychostimulants and opioids, while having minimal effect on D1 neurons.

The paper identifies a spatiotemporal dynamic network in the brain associated with depression vulnerability using machine learning and LFP data from stressed mice.