Thomas C. J. Tan

The paper examines how RNA-protein interactions change in memory and cytotoxic T cells under low glucose stress, revealing distinct metabolic and functional responses.

This study improves RNA-interactome detection using DIA SILAC over DDA SILAC, achieving higher protein detection and lower variation with single-shot analysis.

This study shows that eIF5a modification regulates protein translation in CD8 T cells, affecting cytokine production and cell cycle control during activation.