André L. P. Tavares

This study investigates the role of PA2G4, MCRS1, and SOBP as regulators of SIX1+EYA transcriptional activity in mouse mandibular arch neural crest cells, revealing distinct mechanisms of regulation.

The paper uses whole-cell proteomics to identify novel regulators of ciliogenesis in Xenopus multiciliated cells, revealing 832 upregulated proteins involved in ciliary structures and function.

This paper generates a six1-null line in Xenopus tropicalis using CRISPR/Cas9 to study development and congenital disease.

The paper shows Sobp interacts with Six1 in the nucleus, represses its transcriptional activity, and is essential for craniofacial development in Xenopus.

The paper investigates how mutations in SIX1 affect otic gene expression in Xenopus embryos, finding differential impacts on target genes like prdm1 and spry1.