Author

Tony Zheng

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Giovanni StracquadanioiD· 2 shared Hong Seo LimiD· 2 shared Jef D. BoekeiD· 2 shared Jitong Cai· 2 shared Joel S. BaderiD· 2 shared Ju Young AhniD· 2 shared Lauren Meyer· 2 shared LESLIE ANN MITCHELLiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Giovanni StracquadanioORCID

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3 papers

Recent·Most cited

Whole-Cell Proteomics Identifies Novel Regulators of Ciliogenesis Beyond the Axoneme

Xiaolu Xu, Yanbao Yu, Tony Zheng, Fiona Clark, Jean Ross, Neha Sindhu, André L. P. Tavares, John B. Wallingford, Shuo Wei, Jian Sun

The paper uses whole-cell proteomics to identify novel regulators of ciliogenesis in Xenopus multiciliated cells, revealing 832 upregulated proteins involved in ciliary structures and function.

bioRxiv · May 20, 2025 · PreprintDevelopmental Biology

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita, Michael J. Shen, LESLIE ANN MITCHELL, Hikaru Kurasawa, Evgenii Lobzaev, Viola Fanfani, Max A. B. Haase, Xiaoji Sun, Qingwen Jiang, Gregory W. Goldberg, David M. Ichikawa, Stephanie L. Lauer, Laura H. McCulloch, , Jef D. Boeke

This paper synthesizes the largest eukaryotic yeast chromosome, synIV, and investigates how its 3D structure affects gene regulation and transcription.

Molecular Cell · Nov 8, 2023Peer-reviewedSynthetic Biology

Synthetic chromosome fusion: effects on genome structure and function

Jingchuan Luo, Luís A. Vale-Silva, Adhithi R. Raghavan, Guillaume Mercy, Jonna Heldrich, Xiaoji Sun, Mingyu Kenneth Li, Weimin Zhang, Neta Agmon, Kun Yang, Jitong Cai, Giovanni Stracquadanio, Agnès Thierry, Yu Zhao, Camila Coelho, , Jef D. Boeke

The paper synthesizes a shorter yeast chromosome and studies its fusion with other chromosomes, revealing new 3D structural interactions and Red1 binding patterns.

bioRxiv · Aug 10, 2023 · PreprintSynthetic Biology