Nikko‐Ideen Shaidani

Synapse specific alterations of autophagy are a hallmark of Danon disease

This study identifies synapse-specific autophagy alterations in Danon disease using a Xenopus tropicalis model, linking them to visual and cognitive impairments.

The Xenopus respiratory system reveals common tetrapod mechanisms for growth, regeneration and healing

This study identifies conserved molecular mechanisms and stem cells in Xenopus tropicalis lung growth and repair, showing similarities with mammalian systems.

ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing.

The paper shows Adam13 regulates histone modifications, gene expression, and splicing in cranial neural crest cells by interacting with Arid3a and other proteins.

Age associated DNA methylation changes in Xenopus frogs

The paper identifies age-associated DNA methylation changes in Xenopus tropicalis using whole genome bisulfite sequencing and develops a cost-effective epigenetic clock assay.

Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease

This paper generates a six1-null line in Xenopus tropicalis using CRISPR/Cas9 to study development and congenital disease.