Yael Arien

The paper compares outcomes of X-poisoning and X-shredding in malaria mosquitoes by timing Cas9 expression during spermatogenesis, finding that timing determines distortion type.

This paper develops a genetic sexing strain in Aedes albopictus mosquitoes by combining CRISPR-engineered selectable traits with sex conversion, enabling efficient and accurate sex separation.

The paper tests a Y-linked Cas9 expression system in Drosophila melanogaster and finds reduced Cas9 activity, suggesting meiotic sex chromosome inactivation.

The paper develops a genetic tool for Bactrocera zonata by creating a chromosome-level genome and CRISPR/Cas9-induced white-eye mutants to aid in Genetic Sexing Strain development.

This study investigates X-poisoning gene drives in mosquitoes, finding that sex distortion is mainly due to loss of X-bearing sperm rather than postzygotic lethality.