Li-Zhi Mi

This study identifies the structural basis for PINK1 maturation by the HSP90/CDC37/FKBP51 chaperone complex and shows FKBP51 negatively regulates PINK1 function in mitophagy.

This study identifies conformational dynamics and dimer formation in TcPINK1, showing their role in Parkin recruitment and mitophagy.

The paper identifies multiple allosteric mechanisms regulating PDGFRβ kinase activity and shows their conservation in other type III RTKs, with implications for disease.