Author

Véronique Lefèbvre

Children's Hospital of PhiladelphiaORCID 0000-0001-9916-8433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Akira Suto· 1 shared Arifumi IwataiD· 1 shared Camille E. M Piquet· 1 shared David MerrickiD· 1 shared Hiroshi NakajimaiD· 1 shared Josephine M. E. TaniD· 1 shared Junichi IshikawaiD· 1 shared Karima Drareni· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Akira Suto

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 28, 2026

SOX4 Reprograms Adipose Stromal Cells into a Cancer-Associated Fibroblast-like State to Drive Metabolic Disease

Karima Drareni, Ryan P. Calhoun, Lan Cheng…·Patrick Seale

This study shows that SOX4 reprograms adipose stromal cells into CAF-like cells in obesity, promoting metabolic disease through TGFβ and MDK signaling.

DOI 10.64898/2026.09.24.754142

mousehuman

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 4, 2025

Sox4 in Treg Cells Suppresses IL-10 Production via c-Maf Degradation and Exacerbates Type 2 Inflammation

Yuki Hayashi, Kensuke Suga, Akira Suto…·Hiroshi Nakajima

This study identifies Sox4 as a suppressor of IL-10 production in Treg cells by degrading c-Maf, leading to exacerbated type 2 inflammation in asthma models.

DOI 10.1101/2025.11.04.686669

mousebulk RNA-seq

𝕏 PostBluesky