Molecular BiologyComputational and Structural Biotechnology JournalPeer-reviewed
Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death
Michael A. Margreiter, Monika Witzenberger, Yasmine Wasser…·Giulia Rossetti
The paper identifies and validates small-molecule inhibitors of TRMT2A that reduce polyQ aggregation and cell death in human cells.
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