Author

Monika Witzenberger

Helmholtz MunichORCID 0000-0002-9576-3523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron VoigtiD· 1 shared Andrzej Chramiec‐GłąbikiD· 1 shared Anna BielaiD· 1 shared Anneke BrümmeriD· 1 shared Athéna SkliasiD· 1 shared Benedetta Poma· 1 shared Carina Sobisch· 1 shared Claudia BagniiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Aaron VoigtORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pus7 mutation links tRNA dysregulation to aggressive behavior through activation of the integrated stress response and glycolytic reprogramming

Michael Stock, Maria Guillen-Angel, Monika Witzenberger, Jakub Nowak, Anna Biela, Andrzej Chramiec‐Głąbik, Vittoria Mariano, René Dreos, Athéna Sklias, Manfredo Quadroni, Anneke Brümmer, Héctor Gallart‐Ayala, Julijana Ivanišević, Nicolas Guex, Leon Kleenman, , Jean‐Yves Roignant

The paper shows that Pus7 mutations reduce tRNA-Asp levels, activating the integrated stress response and glycolytic reprogramming, which contributes to aggressive behavior.

bioRxiv · May 12, 2025 · PreprintGenetics

Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death

Michael A. Margreiter, Monika Witzenberger, Yasmine Wasser, Elena Davydova, Robert Janowski, Jonas Metz, Pardes Habib, Sabri E. M. Sahnoun, Carina Sobisch, Benedetta Poma, Oscar Palomino‐Hernández, Mirko Wagner, Thomas Carell, Nadim Jon Shah, Jörg Bernhard Schulz, , Giulia Rossetti

The paper identifies and validates small-molecule inhibitors of TRMT2A that reduce polyQ aggregation and cell death in human cells.

Computational and Structural Biotechnology Journal · Dec 28, 2021Peer-reviewedMolecular Biology