Author
Forschungszentrum JülichORCID 0000-0002-0428-7462Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Robin A. Karge, Florian P. Fischer, Hannah Schüth…·Stefan Wolking
This study models AP2M1-DEE in Drosophila, finding heat-sensitive paralysis, altered neuron morphology, and seizure resistance, suggesting developmental defects over synaptic dysfunction.
Marina L. García‐Vaquero, M. Heim, Bàrbara Flix…·Margarida Gama‐Carvalho
The paper identifies convergent functional impacts of SMA and ALS genes on neuronal protein complexes in Drosophila models, suggesting shared mechanisms in motor neuron degeneration.
Michael A. Margreiter, Monika Witzenberger, Yasmine Wasser…·Giulia Rossetti
The paper identifies and validates small-molecule inhibitors of TRMT2A that reduce polyQ aggregation and cell death in human cells.