Damià Romero–Moya

This paper characterizes DO1Cas9, a cold-adapted Cas9 nuclease from the deep ocean, showing improved activity under cold conditions and broader organismal applicability.

TRU-PE improves prime editing efficiency and scalability for genome engineering in human cells, enabling multi-locus edits and a platform for studying genetic disorders.

This study shows that STAU2 regulates human neurogenesis by affecting transcription factors, miRNA control, and progenitor maintenance, leading to changes in neural differentiation and organoid development.

This study maps the differentiation trajectory of iPSCs to hepatic stellate cells, identifying RORA as a key regulator of metabolic reprogramming and fibrosis.