Cecily C. Midkiff

This study uses a mouse model to show that rapid podocyte ablation leads to acute renal tubule cell necrosis, interstitial fibrosis, and renal failure.

This study shows that SIV infection in rhesus macaques leads to increased p16 and decreased SIRT1, associated with neurodegeneration and aging markers in multiple brain regions.

This study examines how antiretroviral therapy (ART) affects macrophage movement in and out of the CNS in SIV-infected macaques, showing ART reduces perivascular macrophage accumulation but not meningeal or choroid plexus macrophages.

The nonhuman primate model mirrors the epidemiology of human congenital CMV (cCMV) after primary infection and reveals its transmission bottlenecks.

This study identifies key structural elements in the extracellular, hinge, and transmembrane domains of an anti-HIV CAR construct that affect surface expression and cytotoxic activity.