Author

Ahmad A. Saied

Tulane UniversityORCID 0000-0002-3944-7112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:rat· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Robert V. BlairiD· 2 shared Adam Myers· 1 shared Alexandra BlaneyiD· 1 shared Alison R. Van ZandtiD· 1 shared Andrew G. MacLeaniD· 1 shared Anna T. Brown· 1 shared Anne LeiD· 1 shared Brandon F. KeeleiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Robert V. BlairORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART

Yilin Chen, Xiaofeng Ding, Sonalika Ray, Siva Thirugnanam, Robert V. Blair, Ahmad A. Saied, Sergiy Sukhanov, Jay K. Kolls, W. Y. KIM, Patrice Delafontaine, Jay Rappaport, Xuebin Qin, Namita Rout

This study shows that long-term ART in SIV-infected macaques reduces acute inflammation but maintains chronic macrophage and TLR-driven inflammation linked to vascular damage and aging.

Frontiers in Immunology · Mar 12, 2026Peer-reviewedImmunology

Metabolic reprogramming by caloric restriction enhances acute phase virological control and reduces chronic inflammation in SIV-infected rhesus macaques

Naveen Suresh Babu, Chrysostomos Perdios, Maggie Hallmets, Anna T. Brown, Celeste D. Coleman, Christine M. Fennessey, Carolina Allers, Matilda J. Moström, Pratik Khare, Cissy Zhang, Brandon Smith, Nadia Golden, Adam Myers, Lara A. Doyle‐Meyers, Alexandra Blaney, , Joseph C. Mudd

This study shows that caloric restriction in SIV-infected rhesus macaques reduces acute viremia, dampens inflammation, and improves metabolic function, but does not affect viral persistence.

bioRxiv · Mar 12, 2026 · PreprintImmunology

Neuroinvasion by Simian Immunodeficiency Virus Triggers Glial Senescence and Accelerated Neurodegeneration

Miranda D. Horn, Cecily C. Midkiff, Alison R. Van Zandt, Ahmad A. Saied, Andrew G. MacLean

This study shows that SIV infection in rhesus macaques leads to increased p16 and decreased SIRT1, associated with neurodegeneration and aging markers in multiple brain regions.

bioRxiv · Dec 16, 2025 · PreprintNeuroscience