ImmunologybioRxivPreprint
Fast receptor-antigen dissociation kinetics promote CAR-T cell tumor infiltration, functional fitness, and antitumor efficacy in solid tumors
DOI 10.64898/2026.10.10.756030
Author
Nicholas R. J. Gascoigne
National University of SingaporeORCID 0000-0001-9980-4225Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2023-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 18 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- ImmunologybioRxivPreprint
Uni-TINT: Unifying T and Innate Lymphoid Cell Taxonomy with a high resolution, pan-disease and pan-tissue single-cell transcriptomic atlas
Samuel Chuah, Mengwei Li, Kok Siong Ang…·J K Chen
Uni-TINT creates a unified single-cell atlas of T and innate lymphoid cells across diseases and tissues, identifying new cell subtypes and functional associations.
- ImmunologybioRxivPreprint
Themis dominates T cell exhaustion by regulation of TCR and PD-1 signaling
Jian Tang, Xian Jia, Taoling Zeng…·Guo Fu
This study shows Themis regulates T cell exhaustion by controlling TCR and PD-1 signaling, with loss of Themis causing severe immunopathology in chronic viral infection.
2 citations