Jens Lichtenberg

The paper investigates how GBA1 mutations affect glycoprotein nonmetastatic melanoma protein B (GPNMB) expression in dopaminergic neurons, linking lipid accumulation to Parkinson's disease risk.

The paper evaluates the reliability of Gauchian for detecting GBA1 variants in whole genome sequencing, finding it misses some rare mutations and misreports genotypes due to database limitations.

The paper evaluates the NeuroBooster array's performance in genotyping pathogenic variants in Parkinson's disease across ancestries and validates their frequencies in diverse populations.

This study identifies conserved and species-specific cis-regulatory elements in human and mouse blood cells using integrative epigenomic analysis and clustering.

This study shows that MRP5 and MRP9 work together in male reproduction and mitochondrial function through their localization to mitochondrial-associated membranes and their roles in heme transport and metabolic regulation.

The paper integrates epigenomic and transcriptomic data from mouse hematopoiesis to identify regulatory elements and their dynamics across cell types.

The paper integrates GATA transcription factors and epigenomes in mouse hematopoietic cells using IDEAS to map regulatory landscapes and identify candidate cis-regulatory elements.