Author

Richard Sam

New York UniversityORCID 0000-0002-2107-0329Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Eric KlanniD· 2 shared Mauricio Martins OliveiraiD· 2 shared Alejandro Martín‐ÁvilaiD· 1 shared Amy X. Guo· 1 shared Carson C. Schultz· 1 shared Charis Ma· 1 shared Charles J. SheehaniD· 1 shared Chase CheniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Eric KlannORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Astrocytes instructively regulate neuronal translation

Wendy Liu, Carson C. Schultz, Eshaan A Khan, Mauricio Martins Oliveira, Srinidhi Venkatesan Kalavai, Charles J. Sheehan, Xunzhao Zhang, Richard Sam, Eric Klann

This study shows astrocytes regulate neuronal translation through secreted proteins, with implications for neurodegenerative diseases.

bioRxiv · Jul 28, 2026 · PreprintNeuroscience

Microglia coordinate activity-dependent protein synthesis in neurons through metabolic coupling

Drew I. Adler, Alejandro Martín‐Ávila, Evan Cheng, Mauricio Martins Oliveira, Muxian Zhang, Harrison Tudor Evans, Deliang Yuan, Richard Sam, Nathan Zhang, María Clara Sellés, Olivia Mosto, Wendy J. Liu, Amy X. Guo, Shane Antony Liddelow, Robert C. Froemke, , Eric Klann

The paper shows microglia support neuronal protein synthesis by coordinating metabolic coupling in response to increased demand from motor tasks.

bioRxiv · Oct 29, 2025 · PreprintNeuroscience

Bidirectional regulation of glycoprotein nonmetastatic melanoma protein B by β-glucocerebrosidase deficiency in GBA1 isogenic dopaminergic neurons from a patient with Gaucher disease and parkinsonism

Chase Chen, Charis Ma, Richard Sam, Jens Lichtenberg, Tiffany Chen, Ying Hao, Ziyi Li, Isabelle Kowal, Katherine M. Andersh, Yue Andy Qi, Gani Perez, Ellen Hertz, Yan Li, Darian Williams, Mark J. Henderson, , Yu Chen

The paper investigates how GBA1 mutations affect glycoprotein nonmetastatic melanoma protein B (GPNMB) expression in dopaminergic neurons, linking lipid accumulation to Parkinson's disease risk.

bioRxiv · Jun 23, 2025 · PreprintNeuroscience