Yu Zhang

The paper investigates how RNA structure influences stress granule formation and recovery, showing that single-stranded RNA is preferentially included in stress granules and that RNA-binding proteins and helicases regulate this process.

This study identifies ZFP281 as a coordinator of DNMT3A/3B and TET1 to regulate DNA methylation and gene expression during pluripotent stem cell state transitions.

S3V2-IDEAS normalizes, denoises, and integrates epigenomic data across cell types to identify epigenetic states and signal intensity patterns.

The paper integrates GATA transcription factors and epigenomes in mouse hematopoietic cells using IDEAS to map regulatory landscapes and identify candidate cis-regulatory elements.