Nahid Tayebi

Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism

The paper compares dopaminergic neurons from siblings with Gaucher disease to investigate genetic factors contributing to Parkinsonism.

Is Gauchian genotyping of GBA1 variants reliable?

The paper evaluates the reliability of Gauchian for detecting GBA1 variants in whole genome sequencing, finding it misses some rare mutations and misreports genotypes due to database limitations.

Genome-wide Association Identifies Novel Etiological Insights Associated with Parkinsons Disease in African and African Admixed Populations

Intronic GBA1 variant rs3115534-G, common in African and African admixed ancestry but rare elsewhere, raises Parkinson's disease risk (OR 1.58) and lowers onset age.

Polygenic Parkinson's disease genetic risk score as risk modifier of parkinsonism in Gaucher disease

The paper examines how a polygenic Parkinson's disease genetic risk score modifies the risk of parkinsonism in Gaucher disease patients.

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture

This paper identifies five new genetic risk loci for Lewy body dementia through whole-genome sequencing and shows shared risk profiles with Alzheimer’s and Parkinson’s disease.