Author

Brian A. Hodge

Buck Institute for Research on AgingORCID 0000-0001-6190-9363Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Pankaj KapahiiD· 2 shared Amit Kumar SahuiD· 1 shared Anne PipathsoukiD· 1 shared Bhagawati Jalnapurkar· 1 shared Birgit SchillingiD· 1 shared Charis AmberiD· 1 shared Charles Curt· 1 shared Charles LauiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetics

Pankaj KapahiORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 21, 2023

A deep-learning-based screening platform in aging-relevant human motor neurons to identify therapeutic compounds for amyotrophic lateral sclerosis

Bhagawati Jalnapurkar, David Le, William Shainin…·Jeremy W. Linsley

The paper develops a deep learning platform to screen compounds for ALS treatment using age-relevant human motor neurons and identifies NCB-0846 as a potential therapeutic.

1 citation

humanmouse

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GeneticseLifePeer-reviewedSep 20, 2023

Methylglyoxal-derived hydroimidazolone, MG-H1, increases food intake by altering tyramine signaling via the GATA transcription factor ELT-3 in Caenorhabditis elegans

Muniesh Muthaiyan Shanmugam, Jyotiska Chaudhuri, Durai Sellegounder…·Pankaj Kapahi

This study identifies MG-H1 as a mediator of increased food intake in C. elegans glod-4 mutants through a tyramine signaling pathway regulated by the GATA transcription factor ELT-3.

11 citations

C. elegansstatistical model

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NeurosciencebioRxivPreprintMay 8, 2021

Dietary restriction and clock delay eye aging to extend lifespan in D. melanogaster

Brian A. Hodge, Geoffrey T. Meyerhof, Subhash D. Katewa…·Pankaj Kapahi

This study shows dietary restriction extends lifespan in D. melanogaster by protecting the visual system from age and light-related damage through circadian regulation.

DOI 10.1101/2021.05.08.443272

Drosophilaexperimental assay

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