Intranasal Delivery of Hypoxia Primed Whartons Jelly MSC Derived sEVs Reprograms Neuroimmune Signalling and Ameliorates Behavioural Deficits in a Valproic Acid Induced Mouse Model of Autism Spectrum Disorder
Shruti Mahapatra, Bhanu Teja, Ritesh Kumar Netam…·Sujata Mohanty
This study shows that hypoxia-primed Wharton's jelly MSC-derived sEVs improve behavioral and neuroinflammatory outcomes in a mouse model of ASD through enhanced neuroprotective effects.