Ritu Gupta

This study optimizes the dose and timing of MSC-derived culture-conditioned media (CCM) to enhance its immunomodulatory effects on CD3+ T-cells in acute graft-versus-host disease.

This study develops a 295-gene targeted sequencing panel and an AI model to identify disease-initiating and transformative biomarkers in multiple myeloma.

This study uses machine learning to predict acute Graft-versus-Host-Disease (aGvHD) based on immune cell and cytokine profiles at engraftment, finding high accuracy with cytokine and T-cell data.

This study compares the immunomodulatory effects of hypoxia-preconditioned bone marrow and Wharton's jelly mesenchymal stem cells in acute graft-versus-host disease, finding WJ-MSCsHYP more effective due to enhanced mitochondrial transfer and metabolic reprogramming.

This study shows that hypoxia and apoptosis conditioning of WJ-MSCs enhances their immune regulatory capacity in aGVHD by promoting Treg differentiation and M2 macrophage polarization.

This study compares T-cell responses between healthy donors and aGVHD patients to optimize PHA and IL-2 concentrations for in vitro T-cell proliferation studies.

The paper analyzes SARS-CoV-2 genomic data from India to study the emergence, phylogeny, and evolution of the Omicron BA.2 variant during the third wave, finding its association with comorbid patients and ongoing mutations.

This study identifies two distinct molecular signatures in postmortem lung tissue from severe COVID-19 patients, associated with different pathological mechanisms and microbiome profiles.