Molecular BiologybioRxivPreprint
Osteopontin Upregulation Defines a Pre-Rupture State in Thoracic Aortic Aneurysms in Mice and Humans
Kaori Sugiyama, Yuya Sato, Hiroko Matsunaga…·Haruko Takeyama
The paper identifies osteopontin (OPN) upregulation as a conserved molecular signature of the pre-rupture state in thoracic aortic aneurysms across mice and humans.