Haruko Takeyama

The paper uses single-cell genomics to identify Enterobacterales bacteria in soybean rhizoplane soils associated with red crown rot, showing they carry cationic antimicrobial peptide resistance genes.

The paper identifies osteopontin (OPN) upregulation as a conserved molecular signature of the pre-rupture state in thoracic aortic aneurysms across mice and humans.

This study uses label-free Raman imaging to identify distinct cell populations in human skin, revealing molecular signatures associated with specific epidermal layers and stem cell niches.

The paper establishes an HPV18-associated cervical adenocarcinoma model using iRCs and integrates spatial transcriptomics with single-cell multi-omics to identify Gland_A as a key component with specific molecular features.

The paper uses single-cell genomics to analyze virus-host interactions in freshwater bacteria, revealing differences in infection rates and defense strategies between copiotrophs and oligotrophs.

This study uses a new single-virus sequencing platform to identify diverse viral genomes in river water, revealing novel species and gene transfer patterns.

This study uses polygenic risk scores derived from brain transcriptomic profiles to explain clinical heterogeneity in Alzheimer's disease.

This study develops a sensitive RNA-seq method for FFPE tissues to analyze spatial gene expression in tumor microenvironments.

The paper develops a single-cell genome sequencing platform, SAG-gel, to analyze microbial diversity in Red Sea environments, revealing 734 partial genomes from 231 species, most of which are newly identified.

The paper uses multi-omics data to analyze cross-organism interactions in coral holobionts, revealing host dominance over zooxanthellae and immune responses triggered by Endozoicomonas bacteria.