Yuya Sato

The paper identifies osteopontin (OPN) upregulation as a conserved molecular signature of the pre-rupture state in thoracic aortic aneurysms across mice and humans.

This study uses human striatal-midbrain assembloids to show that α-synuclein pathology spreads from the striatum to midbrain dopaminergic neurons, causing functional impairment.

This paper develops a closed-loop biological neural network system that learns and generates temporal patterns through feedback control, demonstrating adaptability and reduced synchronization.

This study compares vascularization strategies in human cerebral organoids using single-cell RNA sequencing to identify transcriptomic effects and cell interactions.