Anna R. Eitel

Membrane-gated SNARE zippering focuses energy for fusion

This study uses optical tweezers to measure SNARE complex intermediates and energetics during membrane fusion, revealing how membrane forces, lipids, and regulatory proteins control the process.

Architecture of the Gβγ-prefusion SNARE complex reveals the molecular mechanism of inhibition of vesicle fusion

The paper determines the structure of the Gβγ-prefusion SNARE complex using cryo-EM and proposes a model for how Gβγ inhibits synaptic vesicle fusion by blocking SNARE complex assembly.

Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: role of a conserved aromatic cage

The paper investigates the role of an aromatic cage in the lipid specificity of Loxosceles α clade phospholipase D enzymes using molecular dynamics simulations and experimental validation.