Zhiqun Xi

This study uses optical tweezers to measure SNARE complex intermediates and energetics during membrane fusion, revealing how membrane forces, lipids, and regulatory proteins control the process.

This study identifies TUG's role in maintaining the ERGIC as a distinct organelle by organizing anterograde trafficking and preventing membrane homeostasis disruption.

This paper introduces genetically encoded mechano-sensors using coiled coils to measure mechanical forces in vivo with diverse readouts and compact design.