Author

Sonia I. Barroso

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-0062-2016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrés AguileraiD· 2 shared Aleix Bayona‐FeliúiD· 1 shared Amador Romero-FrancoiD· 1 shared Angela GalloiD· 1 shared Cristina CeredaiD· 1 shared Daisy SprovieroiD· 1 shared Domenico Alessandro SilvestrisiD· 1 shared Fernando Mejías-NavarroiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Andrés AguileraORCID

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2 papers

Recent·Most cited

ADAR2-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

Sonia Jimeno, Rosario Prados‐Carvajal, María Jesús Fernández-Ávila, Sonia de Regules Silva, Domenico Alessandro Silvestris, Martín Endara-Coll, Guillermo Rodríguez‐Real, Judit Domingo‐Prim, Fernando Mejías-Navarro, Amador Romero-Franco, Silvia Jimeno-González, Sonia I. Barroso, Valeriana Cesarini, Andrés Aguilera, Angela Gallo, , Pablo Huertas

The paper shows that ADAR2-mediated RNA editing of DNA:RNA hybrids is essential for DNA double strand break repair by facilitating DNA end resection.

Nature Communications · Sep 17, 2021Peer-reviewedGenetics

TDP-43 deficiency links Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage

Marta Giannini, Aleix Bayona‐Feliú, Daisy Sproviero, Sonia I. Barroso, Cristina Cereda, Andrés Aguilera

This study shows that TDP-43 deficiency leads to R-loop accumulation and DNA damage, linking ALS pathology to R-loop homeostasis.

PLoS Genetics · Dec 10, 2020Peer-reviewedMolecular Biology