Cell BiologyScience AdvancesPeer-reviewed
Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux.
Anthony W. Martinelli, Chun-Pei Wu, Tristan Vornbäumen…·James A. Nathan
The paper identifies SETD2 as a regulator of iron metabolism by modulating ferritin breakdown, affecting cellular iron levels and ferroptosis resistance.
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