Kyung-Tae ‍Lee

This study identifies Pro3 as a key enzyme linking proline biosynthesis to cell wall integrity in Cryptococcus neoformans, showing its critical role in virulence and growth.

The paper identifies the protein phosphatase 2C domain of adenylyl cyclase in Cryptococcus neoformans as essential for its pathobiological functions, affecting virulence and immune response.

The paper identifies essential transcriptional regulators in Cryptococcus neoformans, highlighting Ezt1 as a key regulator of growth, drug response, and virulence.

This study systematically mutagenizes histones in Cryptococcus neoformans to show their role in maintaining 3D chromosome architecture and virulence.

The paper identifies Wcp1, a WD40 protein with cyclophilin domains, as essential for CO2/heat tolerance and acidic pH adaptation in Cryptococcus neoformans, linking these functions to virulence.

This study identifies the calcineurin pathway's role in regulating thermotolerance, cell integrity, antifungal resistance, and virulence in Candida auris through genetic deletion and transcription factor analysis.

This study identifies a link between calcineurin, the amino acid permease Byc1, and protein kinase A in Cryptococcus neoformans, showing their roles in thermotolerance and antifungal drug resistance.