Author

Soo Chan Lee

Texas Tech UniversityORCID 0000-0002-7792-5947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Alejandro L. AntoniaiD· 1 shared Ambro van HoofiD· 1 shared Andy Ingham· 1 shared Anusha M. Gopalakrishnan· 1 shared Bhawana IsraniiD· 1 shared Courtney P. Cornitius· 1 shared Daniel Bahn· 1 shared Danielle A. GarsiniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenetics

Alejandro L. AntoniaORCID

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3 papers

Recent·Most cited

Characterization of tRNA ligase function in pathogenic fungi and trypanosomes reveals the ligase domain as a promising drug target

Khondakar Sayef Ahammed, Pedro Miramón, Lukas Schrettenbrunner, Melissa R. Cruz, Eun Young Huh, Huiqing Hu, Bhawana Israni, Hannah B. Wilson, Ziyin Li, Soo Chan Lee, Matthew G. Blango, Danielle A. Garsin, Michael C. Lorenz, Ambro van Hoof

The paper identifies the Trl1 sealing domain as a promising drug target for antifungal and anti-trypanosomal therapies by analyzing its essentiality in pathogenic fungi and trypanosomes.

bioRxiv · Aug 20, 2026 · PreprintMolecular Biology

The amino acid permease Byc1 is involved in calcineurin-dependent thermos-tolerance in Cryptococcus neoformans

Kyung-Tae ‍Lee, Madeline Giner, Daniel Bahn, Courtney P. Cornitius, Soo Chan Lee

This study identifies a link between calcineurin, the amino acid permease Byc1, and protein kinase A in Cryptococcus neoformans, showing their roles in thermotolerance and antifungal drug resistance.

bioRxiv · Feb 27, 2024 · PreprintMicrobiology

An atlas of genetic variation for linking pathogen-induced cellular traits to human disease

Liuyang Wang, Kelly J. Pittman, Jeffrey R. Barker, Raul Salinas, Ian B. Stanaway, Graham D. Williams, Robert J. Carroll, Tom Balmat, Andy Ingham, Anusha M. Gopalakrishnan, Kyle D. Gibbs, Alejandro L. Antonia, The eMERGE Network, Joseph Heitman, Soo Chan Lee, , Dennis C. Ko

The paper links genetic variation to pathogen-induced cellular traits and disease by integrating GWAS data with clinical and experimental validation.

Cell Host & Microbe · Aug 1, 2018Peer-reviewedGenetics