Nobutaka Hirokawa

The paper identifies the Hitchdock domain in kinesin-2 tail as critical for adaptor assembly and cargo binding, revealing its structural role in interactions with KAP3 and APC.

This study shows KIF5B is essential for glucose-stimulated insulin secretion by facilitating CaV1.2 channel folding in the ER, maintaining glucose homeostasis in mice.

The paper shows that leftward transfer of PKD1L1 polycystin channels initiates left-dominant calcium signaling in mouse embryos, linking nodal flow to laterality.