Isabelle Gaugué

This study identifies three distinct mechanisms by which Xrp1 is induced in response to different stresses in Drosophila, highlighting its role in the Integrated Stress Response.

The paper shows that tissue mechanics, not gene patterning, determine the scaling of collective cell migration velocity with tissue size during development.

The paper introduces a framework to integrate spatial transcriptomics with live morphometrics to infer gene regulatory networks and validate gene function in Drosophila thorax development.

This study shows that Drosophila wing discs continue growing during the larva-to-pupa transition and undergo growth arrest later in the pupal period, involving a switch that uncouples proliferation from tissue growth.

The paper identifies biallelic variants in ARHGAP19 as a cause of motor-predominant neuropathy with conduction slowing in multiple families.

The paper shows how curvature and tension in Drosophila homeotic compartments drive spatiotemporal folding during development.

The paper investigates homologous chromosome pairing in Drosophila males, showing that despite lacking synaptonemal complexes and recombination, pairing occurs via SC proteins, the SUN/KASH complex, and microtubules, with slower dynamics compensated by longer cell cycles.