Author
National Institutes of HealthORCID 0000-0002-0120-2814Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Annika L. Gustafson, Stephanie Nance, Berkley E. Gryder…·Adam David Durbin
The paper identifies a core regulatory circuit in rhabdomyosarcoma and shows that targeting two co-activators synergistically inhibits tumor growth.
Elizabeth Alexandra Cooper, David A Posner, Colin Y.C. Lee…·Richard J. Gilbertson
This study identifies a mechanism by which skull bone marrow-derived HSPCs and CD4+ T cells promote immunotolerance in childhood brain tumours, showing that antibody therapy targeting CSF cytokines can disrupt this process and induce tumour regression.
Elizabeth A. Mendes, Aanandi Munshi, Archana Singh…·Corinne Mary Linardic
This study identifies RUNX2 as a druggable target in fusion-positive rhabdomyosarcoma, showing its inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and reduces tumor growth.