Author

Sara S. Oltra

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-0128-6106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Gema Moreno‐BuenoiD· 2 shared Alba Orantes· 1 shared Alberto HernándeziD· 1 shared Ana M. LluchiD· 1 shared Ana Reina-Bando· 1 shared Ángela Molina-Crespo· 1 shared Cristina González-ParamosiD· 1 shared David Ros‐PardoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Gema Moreno‐BuenoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 11, 2025

FGFR1 inhibition prevents metabolic adaptation associated with therapy resistance in glioblastoma

Laura Zarzuela, Ignacio G. López-Cepero, Kevin M. Rattigan…·Raúl V. Durán

This study identifies FGFR1 as a key driver of TMZ resistance in GBM through metabolic rewiring and cell cycle regulation, showing that FGFR1 inhibition restores TMZ sensitivity in preclinical models.

DOI 10.1101/2025.01.11.632515

humanbulk RNA-seq

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Molecular BiologyCell Death and DifferentiationPeer-reviewedMar 10, 2023

Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells.

Sara S. Oltra, Sara Colomo, Laura Sin…·Gema Moreno‐Bueno

This study identifies how different GSDMB isoforms and protease cleavage regulate pyroptosis and mitochondrial damage in cancer cells.

87 citationstop 1%

humanexperimental assay

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