Author

Heiner C. Bucher

University of BaselORCID 0000-0002-0131-7873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andri RauchiD· 3 shared Enos BernasconiiD· 3 shared Huldrych F. GünthardiD· 3 shared Jacques FellayiD· 3 shared Matthias EggeriD· 3 shared Matthias L. CavassiniiD· 3 shared Matthieu PerreauiD· 3 shared Michael HuberiD· 3 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Andri RauchORCID

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3 papers

Recent·Most cited

A phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits

Sarah Nadeau, Christian Wandall Thorball, Roger D. Kouyos, Huldrych F. Günthard, Jürg Böni, Sabine Yerly, Matthieu Perreau, Thomas Klimkait, Andri Rauch, Hans Hellmuth Hirsch, Matthias L. Cavassini, Pietro Vernazza, Enos Bernasconi, Jacques Fellay, Venelin Mitov, , S Yerly

This paper introduces a phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits, showing improved detection of host genetic variants in simulations and applied to HIV-1 data.

Molecular Biology and Evolution · Aug 1, 2022Peer-reviewedGenetic & Genomic Medicine

Increased CHIP Prevalence Amongst People Living with HIV

Alexander G. Bick, Konstantin Popadin, Christian W. Thorball, Md Mesbah Uddin, Markella V. Zanni, Bing Yu, Matthias Cavassini, Andri Rauch, Philip Tarr, Patrick Schmid, Enos Bernasconi, Huldrych F. Günthard, Peter Libby, Eric Boerwinkle, Paul J. McLaren, , S. Yerly

The paper investigates the prevalence of clonal hematopoiesis of indeterminate potential (CHIP) in people living with HIV and finds a higher prevalence compared to controls.

Scientific Reports · Jan 12, 2022Peer-reviewedGenetic & Genomic Medicine

The influence of human genetic variation on Epstein-Barr virus sequence diversity

Sina Rüeger, Christian Hammer, Alexis Loetscher, Paul J. McLaren, Dylan Lawless, Olivier Naret, Nina Khanna, Enos Bernasconi, Matthias L. Cavassini, Huldrych F. Günthard, Christian R. Kahlert, Andri Rauch, Daniel Pearce Depledge, Sofia Morfopoulou, Judith Breuer, , Sabine Yerly

The paper investigates how human genetic variation influences Epstein-Barr virus (EBV) sequence diversity by analyzing paired viral and human genomic data from HIV-coinfected individuals.

Scientific Reports · Feb 25, 2021Peer-reviewedGenetic & Genomic Medicine