Huldrych F. Günthard

The paper identifies rare twin cysteine residues in HIV-1 Env V1 linked to neutralization escape and breadth development.

This study assesses how HIV-1 broadly neutralizing antibodies (bnAbs) respond to Env conformational changes by screening mutants, revealing variation in potency based on epitope and Env flexibility.

The paper introduces the XbnAb cohort, a large cohort of 305 people with HIV-1 broadly neutralizing antibody activity, to support HIV vaccine research.

This paper introduces a phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits, showing improved detection of host genetic variants in simulations and applied to HIV-1 data.

The paper investigates the prevalence of clonal hematopoiesis of indeterminate potential (CHIP) in people living with HIV and finds a higher prevalence compared to controls.

The paper investigates how human genetic variation influences Epstein-Barr virus (EBV) sequence diversity by analyzing paired viral and human genomic data from HIV-coinfected individuals.

The paper develops a tool to accurately reconstruct whole HIV genomes from short-read data by using tailored references, showing improved accuracy over standard references.