Author
University of California San DiegoORCID 0000-0002-0139-0210Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Tamar Basiashvili, Joshua Hutchings, Siyu Chen…·Elizabeth Villa
This study uses in-cell cryo-electron tomography to compare how type I and type II kinase inhibitors affect LRRK2-I2020T filament formation and microtubule association in cells.
Eva Pauline Karasmanis, Siyu Chen, Farhaz Shaikh…·Samara L. Reck‐Peterson
This study characterizes the molecular architecture of tunneling nanotubes (TNTs) using live-cell imaging and cryo-ET, revealing a complex structure with actin, microtubules, and organelles.
Kendrick H V Nguyen, Eva Pauline Karasmanis, Agnieszka A. Kendrick…·Andrés E. Leschziner
The paper uses cryo-EM to identify an early intermediate state in dynein activation by LIS1, termed Pre-Chi, and shows its functional importance through mutational analysis.
Agnieszka A. Kendrick, Kendrick H V Nguyen, Wen Ma…·Andrés E. Leschziner
The paper uses cryo-EM to visualize intermediate states of dynein activation pathway by analyzing structures of dynein and dynein-Lis1 bound to ATP.