Author

Gorka Pereira‐Castelo

University of the Basque CountryORCID 0000-0002-0141-8295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:behavioral assay· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Iker Bengoetxea de TenaiD· 2 shared Iván ManueliD· 2 shared Jonatan Martínez‐GardeazabaliD· 2 shared Marta Moreno‐RodrígueziD· 2 shared Rafael Rodríguez‐PuertasiD· 2 shared Alberto Llorente‐OvejeroiD· 1 shared Ángel R. de LeraiD· 1 shared Ángel Torres-MozasiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPharmacology & Toxicology

Iker Bengoetxea de TenaORCID

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2 papers

Recent·Most cited

Synthesis and pharmacological characterization of UVI3502, a novel cannabinoid receptor 1 (CB1) antagonist/inverse agonist

Iker Bengoetxea de Tena, Gorka Pereira‐Castelo, Jonatan Martínez‐Gardeazabal, Marta Moreno‐Rodríguez, Iván Manuel, Claudio Martínez, Belén Vaz, Javier González-Ricarte, Rosana Álvarez, Ángel Torres-Mozas, Francesca Peccati, Gonzalo Jiménez‐Osés, Ángel R. de Lera, Rafael Rodríguez‐Puertas

This paper synthesizes and characterizes UVI3502, a novel CB1 receptor antagonist/inverse agonist, showing high affinity for CB1 and low affinity for CB2, with potential interactions with GPR55.

ACS Omega · Jun 2, 2025Peer-reviewedPharmacology & Toxicology

Cannabinoid agonist WIN55,212-2 prevents scopolamine-induced impairment of spatial memory

Marta Moreno‐Rodríguez, Iker Bengoetxea de Tena, Jonatan Martínez‐Gardeazabal, Gorka Pereira‐Castelo, Alberto Llorente‐Ovejero, Iván Manuel, Rafael Rodríguez‐Puertas

This study shows that WIN55,212-2 prevents scopolamine-induced spatial memory impairment by increasing cannabinoid receptor density and muscarinic tone in cortical areas.

European Journal of Pharmacology · Apr 17, 2025Peer-reviewedPharmacology & Toxicology