Author

Frédéric Koch

Max Planck Institute for Molecular GeneticsORCID 0000-0002-0142-2411Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bernhard G. HerrmanniD· 3 shared Lars WittleriD· 3 shared Manuela Scholze‐Wittler· 3 shared Dennis SchifferliD· 2 shared Jesse V. VeenvlietiD· 2 shared Milena PustetiD· 2 shared Abhishek Sampath KumariD· 1 shared Adriano BolondiiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersDevelopmental Biology

Bernhard G. HerrmannORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 19, 2025

Targeted sex ratio distortion in the mouse

Hermann Bauer, Frédéric Koch, Bettina Lipkowitz…·Bernhard G. Herrmann

The paper describes a method to achieve targeted sex ratio distortion in mice using a selfish supergene component, resulting in a high prevalence of non-transgenic offspring of the desired sex.

DOI 10.1101/2025.06.19.660540

mouseexperimental assay

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Developmental BiologybioRxivPreprintJun 21, 2023

Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse

Dennis Schifferl, Manuela Scholze‐Wittler, Alba Villaronga Luque…·Bernhard G. Herrmann

The paper identifies thousands of notochord enhancers, including TNE2, using ATAC-seq and in vitro models, showing their role in T expression and tail development in mouse embryos.

2 citations

mouseATAC-seq

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Developmental BiologySciencePeer-reviewedDec 10, 2020

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

Jesse V. Veenvliet, Adriano Bolondi, Helene Kretzmer…·Bernhard G. Herrmann

The paper describes a method to generate trunk-like structures from mouse embryonic stem cells that mimic embryonic development features.

333 citationstop 1%

mousescRNA-seq

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