Bernhard G. Herrmann

Acquisition of ampliconic sequences marks a selfish mouse t-haplotype

The paper identifies ampliconic sequences in mouse t-haplotypes as drivers of selfish transmission, showing their evolutionary relationship to sex chromosome dynamics.

Targeted sex ratio distortion in the mouse

The paper describes a method to achieve targeted sex ratio distortion in mice using a selfish supergene component, resulting in a high prevalence of non-transgenic offspring of the desired sex.

The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury

This study identifies the lncRNA Sweetheart as essential for compensatory cardiac hypertrophy after myocardial injury, working synergistically with NKX2-5.

Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse

The paper identifies thousands of notochord enhancers, including TNE2, using ATAC-seq and in vitro models, showing their role in T expression and tail development in mouse embryos.

Fendrr synergizes with Wnt signalling to regulate fibrosis related genes during lung development via its RNA:dsDNA Triplex Element

The paper shows that Fendrr's triplex forming sequence is important for regulating fibrosis-related genes during lung development, and that Fendrr works with Wnt signaling to control these genes.

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

The paper describes a method to generate trunk-like structures from mouse embryonic stem cells that mimic embryonic development features.