PhysiologybioRxivPreprint
EZH2 coordinates inflammatory and pain-associated pathways across joint compartments in osteoarthritis
Sybille Brochard, Alison Vanlaeys, Mahdia Taieb…·Catherine Baugé
This study shows EZH2 inhibition reduces cartilage damage, synovial inflammation, and pain in OA by modulating inflammatory, neuroimmune, and osteoimmune pathways.