Author

Darina Paprčková

University of LausanneORCID 0000-0002-0151-4797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ondřej ŠtěpánekiD· 3 shared Ales DrobekiD· 2 shared Anna KratochvilovaiD· 2 shared Juraj MichalikiD· 2 shared Michaela PřibíkováiD· 2 shared Peter DráberiD· 2 shared Tereza ŠemberováiD· 2 shared Veronika CimermanovaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Ondřej ŠtěpánekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Distinct activation programs in naive and memory CD8 T cells govern stemness and effector persistence of their progeny

Eva Šályová, Darina Paprčková, Juraj Michalik, Veronika Niederlová, Veronika Cimermanova, Kateřina Tomicová, Ales Drobek, Vojtech Racek, Alena Moudrá, Anna Kratochvilova, Michaela Krupková, Radislav Sedláček, Ondřej Štěpánek

The paper shows that prior antigen exposure redirects CD8 T-cell activation programs, shaping progeny fate and persistence through distinct stemness and effector programs in naive and memory cells.

bioRxiv · Sep 10, 2026 · PreprintImmunology

T cells restrain inflammation driven by TNF-induced cell death

Michaela Přibíková, Darina Paprčková, Daniela Knizkova, Alzbeta Synackova, Tereza Šemberová, Ales Drobek, Veronika Niederlová, Juraj Michalik, Anna Kratochvilova, Ondřej Štěpánek, Peter Dráber

This study shows that TANK and AZI2 prevent excessive inflammation by limiting Treg expansion and RIPK1-mediated cell death.

bioRxiv · Apr 23, 2026 · PreprintImmunology

CMTM6 suppresses cell-surface expression of death receptor FAS in mice but not in humans

Tereza Šemberová, Michaela Přibíková, Veronika Cimermanova, Tijana Trivić, Rafik Haderbache, Darina Paprčková, Luca Christen, Helena Kissiova, Ondřej Štěpánek, Peter Dráber

The paper shows that CMTM6 suppresses FAS expression in mice but not humans, highlighting species differences in CMTM6-FAS interaction.

EMBO Reports · Feb 3, 2026Peer-reviewedImmunology